[Human warts by Papovavirus. Clinical, histological and ultrastructural correation]

A clinical, histological and ultraestructural study of 6 cases of epidermodisplacia verruciforme (E.V.). A comparisson with comun warts, plane warts and condilomas are made from this study. The authors attain the conclusion that the E.V. is a precancerous genodermatose in which there is special susceptibility in face to Papova virus group. The E.V. has a typical histological and ultraestructural picture quite diferent from those of the warts. The main characteristic in the presence of an intranuclear vacuole visible at the conventional microscope which is also seen at the electronic microscopy. This vacuole is composed by fibrilar materia and has a peripheric um in which is possible to see abundant viruses. The authors make the first description of intranuclear inclusion in the E.V. Some clinico-evolutive and histological pecularities are underlined in the epidermodisplastia carcinomas. The authors sugest the possibility that the different Papova human tumors could be caused by different Kinds of virus.