[Dysphonia as the first sign of myasthenia gravis]

Ten cases of myasthenia are presented in which dysphonia was the initial sign. Isolated signs of dysphonia continued for several months or years, presenting diagnostic difficulties. Eventually neurologic examination followed by electrophysiological investigation (classical repetitive nerve stimulation and single fibre EMG) as well as edrophonium test allowed proper diagnosis of myasthenia, then confirmed by the clinical course. A possible diagnosis of myasthenia should be taken into consideration in cases with isolated dysphonic signs of uncertain origin.