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Mood stabilizers and anticonvulsants

R A Kowatch1, J P Bucci

  • 1Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, USA. kowatch@utsw.swmed.edu

Pediatric Clinics of North America
|January 13, 1999
PubMed
Summary

This article offers clinicians a guide to mood stabilizers for treating children and adolescents with mood and behavior disorders. It covers diagnosis, treatment, and medication details for conditions like bipolar disorder.

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Area of Science:

  • Pediatric Psychiatry
  • Neuropharmacology
  • Child and Adolescent Psychology

Background:

  • Mood stabilizers are frequently used for pediatric mood and behavior disorders.
  • Effective treatment of pediatric bipolar disorder and conduct disorder requires understanding mood stabilizers.
  • Aggressive behavior in mentally retarded youth may also benefit from mood stabilizers.

Purpose of the Study:

  • To provide clinicians with a working knowledge of mood stabilizers for pediatric use.
  • To detail the mechanisms, pharmacokinetics, dosing, and interactions of mood stabilizers.
  • To present information on diagnosing and treating child and adolescent mood disorders where mood stabilizers are beneficial.

Main Methods:

  • Literature review of mood stabilizers in pediatric populations.
  • Synthesis of information on pharmacologic properties and clinical applications.
  • Discussion of diagnostic criteria and treatment strategies for relevant disorders.

Main Results:

  • Mood stabilizers are effective in treating pediatric bipolar disorder, conduct disorder, and aggressive behavior in intellectually disabled youth.
  • Comprehensive information on drug actions, absorption, distribution, metabolism, excretion, and dosing is provided.
  • Specific guidance on the application of mood stabilizers for various child and adolescent mood and behavior disorders is presented.

Conclusions:

  • Mood stabilizers are essential therapeutic agents for managing specific pediatric mood and behavior disorders.
  • Clinicians require detailed knowledge of mood stabilizers for optimal patient care.
  • This article serves as a resource for understanding and utilizing mood stabilizers in child and adolescent psychiatry.

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