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Related Experiment Videos

Dolicho-vertebrobasilar abnormality and migraine-like attacks

C A Zambrino1, A Berardinelli, A Martelli

  • 1Child Neuropsychiatry Division, 'C. Mondino Foundation' IRCCS, University of Pavia, Italy.mondino@cpbim1.unipv.it

European Neurology
|January 14, 1999
PubMed
Summary

This study investigates dolichobasilar anomaly in two children presenting with severe orbital pain. Findings suggest arterial malformations may compress the trigeminal nerve, causing these pain episodes.

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Area of Science:

  • Neurology
  • Radiology
  • Pediatrics

Background:

  • Dolichobasilar anomaly is a rare vascular condition.
  • Trigeminal neuralgia can manifest with severe facial pain.
  • Magnetic resonance imaging (MRI) and angiography are key diagnostic tools.

Observation:

  • Two pediatric cases with neuroradiologically diagnosed dolichobasilar anomaly were studied.
  • Case 1: A 6-year-old experienced recurrent left orbital pain with photophobia and vomiting.
  • Case 2: A 9-year-old with Marfan syndrome presented with similar nocturnal orbital pain, photophobia, and vomiting.

Findings:

  • Diagnosis in both children was confirmed via MRI and magnetic resonance angiography.
  • The intense, recurrent orbital pain attacks are hypothesized to result from trigeminal nerve compression.

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  • Arterial malformations associated with dolichobasilar anomaly are implicated as the cause of compression.
  • Implications:

    • This study highlights a potential link between dolichobasilar anomaly and trigeminal nerve-related pain in children.
    • Early diagnosis through advanced neuroimaging is crucial for managing such conditions.
    • Understanding this association may improve diagnostic and treatment strategies for pediatric orbital pain.