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Updated: Oct 12, 2026

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
Published on: January 15, 2016
[Agoraphobia and "psychogenic"-attributed gait disorder as symptoms of "stiff-man" syndrome]
M Tesch1, E Severus, B Holdorff
1Neurologischen Abteilung Schlosspark-Klinik, Berlin.
Abstract:
We report on two patients with truncal rigidity and agoraphobia. The fear of crossing open places had been judged as psychogenic in both cases. The detection of positive GAD-antibodies led to our final diagnosis. Treatment with liquorphoresis and clonazepam or diazepam alone resulted in a prompt amelioration of the rigidity and, to a lesser extent, of the agoraphobia as well. The stiff-man syndrome has neurological and psychological aspects and shows one more facet of the syndrome of agoraphobia first described by Westphal.
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