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[Plasma cortisol in neurosurgical resuscitation]
Annales De L'Anesthesiologie Francaise
|January 1, 1976
Summary
This study investigated spontaneous and iatrogenic cortisonemia in neurosurgical patients, analyzing correlations with clinical factors and hydrocortisone dosage. Findings offer insights into cortisol level changes and metabolism in this patient group.
Area of Science:
- Endocrinology
- Neurosurgery
- Clinical Chemistry
Context:
- Spontaneous cortisonemia is a key endocrine marker in neurosurgical patients.
- Understanding cortisol dynamics is crucial for managing these patients.
- Clinical criteria like age and consciousness level may influence cortisol levels.
Purpose:
- To analyze spontaneous cortisonemia in neurosurgical patients.
- To correlate cortisonemia with clinical factors, duration, and nyctohemeral changes.
- To evaluate iatrogenic cortisonemia in response to hydrocortisone and discuss its metabolism.
Summary:
- Spontaneous cortisonemia was measured and correlated with age, etiology, and consciousness level.
- Nyctohemeral variations and duration of hypercortisonism were analyzed.
- Iatrogenic cortisonemia was assessed across increasing hydrocortisone doses, with discussion on cortisol disappearance mechanisms.
Impact:
- Provides baseline data on cortisol levels in neurosurgical patients.
- Enhances understanding of endocrine responses to neurosurgery and steroid treatment.
- Informs clinical practice regarding corticosteroid management and monitoring in neurosurgery.