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Updated: Sep 13, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Atrial thrombosis following the low-energy DC internal countershock of chronic AF: considerations of a clinical
P Palermo1, R Neri, A S Cesario
1Divisione di Cardiologia, Ospedale G.B. Grassi, Roma.
Insights
Cardioversion for atrial fibrillation can cause new thrombus formation, even without prior clots. This study shows a left atrial appendage thrombus regressed spontaneously after cardioversion, highlighting a potential embolic risk.
Area of Science:
- Cardiology
- Cardiac Electrophysiology
Background:
- Embolism risk persists after cardioversion for atrial arrhythmias like atrial fibrillation, even when pre-existing thrombus is absent.
- Atrial stunning and de novo thrombus formation post-cardioversion are proposed mechanisms for embolic events.
Observation:
- A case of chronic atrial fibrillation treated with low-energy internal cardioversion.
- Recurrent heart failure episodes preceded cardioversion.
- A de novo left atrial appendage thrombus formed post-cardioversion, monitored via transesophageal echocardiograms.
Findings:
- The patient developed a new left atrial appendage thrombus after cardioversion.
- No clinical signs of thromboembolism were observed.
- The de novo thrombus resolved spontaneously, confirmed by echocardiography.
Implications:
- This case highlights the potential for de novo thrombus formation after cardioversion, even in the absence of pre-existing thrombus.
- Spontaneous regression of such thrombi is possible, suggesting a dynamic process.
- Further research is needed to understand the mechanisms and clinical significance of post-cardioversion de novo thrombus formation.
Abstract:
Embolism may occur after cardioversion of atrial arrhythmias, especially atrial fibrillation, despite the apparent exclusion of preexisting atrial thrombus. This is related to the now well-known phenomenon of "atrial stunning" following either electrical or pharmacological cardioversion. It has also been suggested that "de novo" atrial thrombus formation after cardioversion could be responsible for the embolic event. We report a case of low-energy internal cardioversion of chronic atrial fibrillation in a patient with recurrent episodes of heart failure followed by a de novo left appendage thrombus formation. The patient, followed clinically and by repeated transesophageal echocardiograms, did not show any clinical sign of thromboembolism and the left appendage thrombus regressed completely, as demonstrated on the transesophageal echocardiogram.
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