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Chronic ulcers and antibiotic treatment
A Tammelin1, C Lindholm, A Hambraeus
1Uppsala, University Hospital, Sweden.
Journal of Wound Care
|January 15, 1999
Summary
This study analyzed 656 chronic wound samples, finding most were colonized by bacteria. Antibiotic resistance among bacterial isolates was notably low, despite some patients receiving antibiotic treatment.
Area of Science:
- Microbiology
- Clinical Medicine
- Infectious Diseases
Background:
- Chronic wounds represent a significant clinical challenge.
- Bacterial colonization is common in chronic wounds, impacting healing.
- Understanding antibiotic resistance patterns is crucial for effective treatment.
Purpose of the Study:
- To investigate the bacterial flora in chronic wounds.
- To analyze antibiotic use and resistance patterns in these patients.
- To assess the prevalence of antibiotic-resistant bacteria in chronic wound infections.
Main Methods:
- Analysis of 656 wound samples from patients with chronic wounds.
- Identification of bacterial species colonizing the wounds.
- Review of antibiotic treatment regimens and resistance profiles.
Main Results:
- High prevalence of bacterial colonization (95.1%) in chronic wounds.
- A significant portion of patients (26%) were undergoing antibiotic treatment.
- Low overall numbers of bacterial isolates exhibiting antibiotic resistance.
Conclusions:
- Chronic wounds frequently harbor diverse bacterial communities.
- Current antibiotic resistance levels in this cohort appear manageable.
- Further research into targeted antibiotic strategies for chronic wounds is warranted.