[Structural heterogeneity of prealbumin fraction rat brain]

Biochemical and immunochemical studies were carried out to prove the structural heterogeneous and supermolecular nature of the rat brain BTB-protein. Microheterogeneity of the BTB-protein--6 subfractions--was found by disc electrophoresis in 30% gel and isoelectric focusing (pH 3-5). Two of the proteins are RNA-proteids. The presence of neurophysin in BTB-protein is suggested. Heterogeneity of BTB-protein according to its antigenic specificity was found by methods of immunodiffusion, immunoelectrophoresis and immunodisc electrophoresis. Heterofunctional complexes are supposed to exist in the nervous tissue which possesses various structural qualities and functional activities within the complex.