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Related Experiment Videos

A phased array echoplanar imaging system for fMRI

Frederick B deB1, L L Wald, L C Maas

  • 1McLean Hospital, Brain Imaging Center, Belmont, MA 02478, USA. frederic@kuru.mclean.org

Magnetic Resonance Imaging
|January 15, 1999
PubMed
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A new phased array receiver system significantly improves signal-to-noise ratio (SNR) in echo-planar imaging (EPI) for brain imaging. This enhances the detection of brain activity and blood volume changes during functional MRI (fMRI) studies.

Area of Science:

  • Neuroimaging
  • Magnetic Resonance Imaging (MRI)
  • Signal Processing

Background:

  • Clinical echoplanar imaging (EPI) requires advanced receiver systems to optimize signal detection.
  • Blood-oxygen-level-dependent (BOLD) and relative cerebral blood volume (rCBV) imaging are crucial for assessing brain function and perfusion.

Purpose of the Study:

  • To evaluate a fully parallel, simultaneous sampling phased array receiver system for BOLD and rCBV experiments.
  • To assess the system's performance compared to conventional surface and head coils.

Main Methods:

  • Development and implementation of a 4-coil phased array receiver system for EPI.
  • Comparison of signal-to-noise ratio (SNR) improvements using the phased array system versus a standard surface coil and a quadrature head coil.

Related Experiment Videos

  • Evaluation of BOLD activation and rCBV mapping in human subjects.
  • Main Results:

    • A 4-coil array around the occipital lobe improved SNR by 1.5x in the visual cortex and 3.1x in the visual association cortex.
    • A 4-coil bilateral array increased head-wide SNR by up to 5x compared to a quadrature head coil.
    • Proportional improvements in the SNR of rCBV maps were observed.

    Conclusions:

    • The developed phased array receiver system offers substantial SNR enhancements for clinical EPI.
    • These improvements lead to better statistical significance and coverage of activation maps in visual cortex studies.
    • The system shows significant potential for advancing functional MRI techniques, including rCBV mapping.