Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Technology for microarray analysis of gene expression

A Watson1, A Mazumder, M Stewart

  • 1Axys Pharmaceuticals 11099 N Torrey Pines Road La Jolla CA 92014, USA. andy_watson@axyspharm.com.

Current Opinion in Biotechnology
|January 16, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advances in diagnostic and therapeutic applications of mismatch repair loss in cancer.

DNA repair·2025
Same author

Towards next generation digital twin in robotics: Trends, scopes, challenges, and future.

Heliyon·2023
Same author

Geographical variation in case fatality rate and doubling time during the COVID-19 pandemic.

Epidemiology and infection·2020
Same author

In-situ electrochemical Fe(VI) for removal of microcystin-LR from drinking water: comparing dosing of the ferrate ion by electrochemical and chemical means.

Journal of water and health·2018
Same author

Second primary malignancies in multiple myeloma: an overview and IMWG consensus.

Annals of oncology : official journal of the European Society for Medical Oncology·2017
Same author

Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic cardiac glycoside UNBS1450 in acute myeloid leukemia.

Leukemia·2016

Microarray technology is versatile for analyzing genomes and measuring gene expression. Recent advancements have improved its robustness, sensitivity, and data analysis capabilities.

Area of Science:

  • Genomics
  • Molecular Biology
  • Biotechnology

Background:

  • Microarray technology has shown significant versatility in the past year.
  • Its application extends to whole model-organism genome analysis.
  • Development of advanced chips for measuring human gene expression has occurred.

Purpose of the Study:

  • To highlight the versatility of microarray technology.
  • To showcase advancements in gene expression analysis.
  • To detail recent technology enhancements.

Main Methods:

  • Analysis of whole model-organism genomes using microarrays.
  • Development of specialized chips for measuring 40,000 human genes.
  • Implementation of noncontact printing methods.

Related Experiment Videos

  • Improved two-color sample preparation techniques.
  • Application of statistically based software for data analysis.

    • Main Results:

    • Demonstrated versatility of microarrays for genome-wide analysis.
    • Successful development of high-density human gene expression chips.
    • Increased robustness and sensitivity of microarray technology.
    • Enhanced data analysis through statistical software.

    Conclusions:

    • Microarray technology has become more robust and sensitive.
    • Advancements in printing, sample preparation, and data analysis have been achieved.
    • The technology is well-suited for comprehensive genomic and gene expression studies.