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Updated: Aug 16, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
[Regular physical activity reduces the risk of cardiovascular disease. Overweight is increasing--we have to
1Karolinska institutet, institutionen för fysiologi och farmakologi, Stockholm. Jan.Henriksson@fyfa.ki.se
Abstract:
Epidemiological findings have shown strong inverse correlation to exist between the level of physical activity and the risk of ischaemic heart disease. Although the mechanism underlying the beneficial effect of physical activity is incompletely understood, available data suggest the risk reduction to be mainly due to decreased development of arteriosclerosis, but that reduced thrombogenesis and myocardial oxygen requirement, and enhanced myocardial vascularisation are contributory factors. In all likelihood, these factors, combined with reduced sympatho-adrenal activity during exercise in the trained state, explain the association of regular physical exercise with a decreased risk of fatal cardiac arrhythmia.
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