Nonsegmental ventilation-perfusion scintigraphy mismatch after radiation therapy
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Updated: Oct 26, 2026
Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment
Published on: August 9, 2024
B B Chin1, J S Welsh, L Kleinberg
1Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA. bchin@rad.jhu.edu
Purpose:
This report illustrates the utility of ventilation-perfusion scintigraphy in differentiating radiation pneumonitis from other causes of dyspnea, including pulmonary embolism, heart failure, obstructive tumor, and chronic obstructive pulmonary disease.
Methods And Results:
A nonsegmental mismatched perfusion abnormality, which exactly conformed to a radiation port, was diagnostic of radiation pneumonitis.
Conclusion:
In patients with lung tumors presenting with dyspnea, ventilation-perfusion scintigraphy may be useful in diagnosing radiation pneumonitis and effectively excluding other causes of dyspnea.
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