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Related Experiment Videos

Hormonal Secretion of Nurses Engaged in Fast-rotating Shift Systems

Costa1, Bertoldi, Kovacic

  • 1Instituto di Medicina del Lavoro, Università di Verona, Servizio di Sorveglianza Sanitaria, Ospedale Policlinico, 37134 Verona, Italy.

International Journal of Occupational and Environmental Health
|July 1, 1997
PubMed
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Fast-rotating shift work, especially night shifts, disrupts nurses' hormonal patterns. Hormones like prolactin and growth hormone show immediate changes, while cortisol and melatonin are more stable.

Area of Science:

  • Endocrinology
  • Occupational Health
  • Chronobiology

Background:

  • Shift work is prevalent in healthcare, particularly in intensive care units.
  • Nurses often work fast-rotating shifts, including consecutive night shifts.
  • Disruptions to circadian rhythms can impact hormonal balance and overall health.

Purpose of the Study:

  • To investigate the impact of fast-rotating shift systems on hormonal patterns in female nurses.
  • To assess the effects of morning, afternoon, and night shifts on specific hormone levels.
  • To differentiate between immediate and adaptive hormonal responses to shift work.

Main Methods:

  • Ten young female nurses in an intensive care unit participated.
  • Plasma cortisol, prolactin, and growth hormone were measured during morning, afternoon, and night shifts.

Related Experiment Videos

  • Urinary excretion of 6-sulfatoxymelatonin (aMT6s), adrenaline, and noradrenaline was determined across shifts.
  • Main Results:

    • Hormones sensitive to external factors (catecholamines, prolactin, growth hormone) exhibited immediate responses during night shifts, indicating a masking effect.
    • Hormones with stronger internal regulation (cortisol, melatonin) maintained more stable patterns.
    • A partial adjustment of cortisol levels was observed during the second night shift.

    Conclusions:

    • Fast-rotating shift work significantly disturbs hormonal patterns in nurses.
    • The type of hormone influences its response to shift work, with some showing immediate masking effects and others greater stability.
    • While some hormonal adaptation may occur, night shifts pose a considerable challenge to maintaining normal physiological rhythms.