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Intramural müllerian papilloma of the vagina
W G McCluggage1, V Nirmala, K Radhakumari
1Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland.
A 24-year-old pregnant woman was found to have a mass in the posterior vagina; a partly cystic and partly solid lesion was excised. Histology showed a papillary mural neoplasm covered by intact squamous epithelium. Immunohistochemical staining showed diffuse positivity with CAM 5.2, EP4, CEA, and EMA and focal immunoreactivity with CA-125. This lesion was interpreted as an intramural mullerian papilloma, only the second such tumor described in the vagina and the first in an adult.
A 24-year-old pregnant woman was found to have a mass in the posterior vagina; a partly cystic and partly solid lesion was excised. Histology showed a papillary mural neoplasm covered by intact squamous epithelium. Immunohistochemical staining showed diffuse positivity with CAM 5.2, EP4, CEA, and EMA and focal immunoreactivity with CA-125. This lesion was interpreted as an intramural mullerian papilloma, only the second such tumor described in the vagina and the first in an adult.