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A sesquiterpene lactone glucoside from Ixeris denticulata f. pinnatipartita
1Pharmanex Shanghai R&D Center, Shanghai Medical University, People's Republic China.
Phytochemistry
|January 19, 1999
Abstract:
An extract from the entire Ixeris denticulata f. pinnatipartita plant afforded the guaianolide sesquiterpene lactone glucoside, 8 beta,15-dihydroxy-1(10),3,11(13)-guaiatrien-12,6-olide-15-O- glucopyranoside, along with the known flavonoids luteolin-7-O-glucoside and luteolin-7-O-glucuronide-6'-methyl ester; their structures were determined by spectroscopic methods. Ixerin Y inhibited the growth of human breast cancer MCF7 and MDA468 cell lines.