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Case study: accidental clonidine patch overdose in attention-deficit/hyperactivity disorder patients

J J Broderick-Cantwell1

  • 1University of Colorado School of Medicine, Denver, USA.

Journal of the American Academy of Child and Adolescent Psychiatry
|January 20, 1999
PubMed

Insights

Transdermal clonidine patches can cause unintentional overdose in children with ADHD. Proper precautions and patient education are crucial for safe clonidine patch use in pediatric patients.

Area of Science:

  • Pharmacology
  • Pediatrics
  • Dermatology

Background:

  • The efficacy and safety of transdermal clonidine depend on the patch's integrity and skin condition.
  • Transdermal clonidine is used to treat pediatric patients with attention-deficit/hyperactivity disorder (ADHD).

Observation:

  • This article details two pediatric cases of unintentional clonidine patch overdose.
  • These are the first reported cases in the literature.

Findings:

  • Pediatric patients with ADHD experienced unintentional overdose due to transdermal clonidine.
  • Factors related to the transdermal system and application site may contribute to overdose.

Implications:

  • Highlights the risk of clonidine toxicity in children using the patch.
  • Emphasizes the need for careful patient education and precautions for safe transdermal clonidine use in pediatric populations.
  • Informs healthcare providers about potential adverse events associated with transdermal clonidine in children.

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