L-cone pigment genes expressed in normal colour vision
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Published on: March 20, 2021
S A Sjoberg1, M Neitz, S D Balding
1Department of Cellular Biology and Anatomy, Medical College of Wisconsin, Milwaukee 53226-0509, USA.
Abstract:
To directly test the hypothesis that only two pigment genes are expressed from the X-chromosome array, we examined expressed M and L pigment gene sequences from > 100 male eye donors. In this sample, there were eight men who expressed high levels of more than one L pigment gene in addition to M pigment genes. The fact that these eyes expressed both L and M pigment genes at significant levels suggests they were from men with normal colour vision. We reject the hypothesis that only two pigment genes from one X-chromosome array can be expressed.
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