[A novel method for measurement of cerebral blood flow in the animal experiment]

A method is described for the measurement of cerebral blood flow by coutinuous registration of the venous out-flow from the temporal sinus of anaesthetized dogs. This method can be used advantageously for the screening of unknown compounds because samples of "cerebral" venous blood are obtained by a less complicated and reliable technique. Changes in cerebral blood flow induced with well defined substances, were registered with our method. The results are discussed.