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Pulmonary disease in the immunocompromised child
D J Pennington1, G J Lonergan, E C Benya
1Department of Radiology, Indiana University Medical Center, Indianapolis 46202-5200, USA.
Journal of Thoracic Imaging
|January 23, 1999
Summary
Children with immune deficiency may have primary syndromes or secondary causes like HIV or chemotherapy. This review covers common childhood immunocompromised states and their complications.
Area of Science:
- Pediatric Immunology
- Immunocompromised States in Children
Background:
- Immune deficiency in children encompasses primary immunodeficiency syndromes and secondary disorders.
- Secondary immunodeficiencies include HIV-associated acquired immunodeficiency and iatrogenic immunosuppression.
Purpose of the Study:
- To discuss common primary and secondary immunocompromised states in childhood.
- To emphasize associated infectious, lymphoproliferative, and neoplastic complications.
Main Methods:
- Review of primary and secondary immunodeficiency states in pediatric populations.
- Emphasis on clinical manifestations and complications.
Main Results:
- Discussion of various causes of childhood immune deficiency.
- Highlighting the spectrum of complications including infections and cancers.
Conclusions:
- Understanding both primary and secondary immune deficiencies is crucial for pediatric care.
- Prompt recognition and management of complications are essential for affected children.