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Portable blood gas and electrolyte analyzer evaluated in a multiinstitutional study
J Lindemans1, P Hoefkens, A L van Kessel
1Department of Clinical Chemistry, University Hospital Rotterdam, 3000 CA Rotterdam, The Netherlands.lindemans@ckcl.azr.nl
Clinical Chemistry
|January 23, 1999
Summary
The SenDx 100 (ABL70) blood gas/electrolyte analyzer demonstrates satisfactory analytical performance for point-of-care testing. Its ease of use and acceptable accuracy meet clinical goals for blood gas and electrolyte analysis.
Area of Science:
- Clinical diagnostics
- Medical instrumentation
- Point-of-care testing
Background:
- The SenDx 100 (now ABL70) is a novel blood gas and electrolyte analyzer designed for rapid, near-patient testing.
- Accurate and efficient analysis of blood gases and electrolytes is crucial for timely clinical decision-making.
Purpose of the Study:
- To evaluate the performance of the SenDx 100 analyzer in multiple clinical settings.
- To compare the SenDx 100's precision, accuracy, and patient-sample results against established laboratory bench analyzers.
Main Methods:
- Multi-center evaluation of the SenDx 100 analyzer.
- Comparison of imprecision and inaccuracy (via tonometry) with three laboratory bench analyzers.
- Analysis of approximately 400 patient blood samples.
Main Results:
- The SenDx 100 showed better performance (lower CVs) for PO2 and potassium, but slightly worse for pH, PCO2, and ionized calcium compared to bench analyzers.
- Overall performance met clinical goals (e.g., CLIA '88) across all participating institutions.
- Mean differences and CVs for patient samples were within acceptable ranges for pH, PCO2, PO2, sodium, potassium, ionized calcium, and hematocrit.
Conclusions:
- The SenDx 100 (ABL70) analyzer exhibits acceptable analytical performance for blood gas and electrolyte measurements.
- Its ease of operation and satisfactory accuracy make it suitable for point-of-care and stat laboratory use.