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Platelet counts in children with iron deficiency anemia
Acta Haematologica
|January 1, 1978
Summary
Children with iron deficiency anemia often have elevated platelet counts. This count normalized with iron therapy, suggesting a link between iron levels and platelet production in pediatric anemia.
Area of Science:
- Pediatric Hematology
- Nutritional Deficiencies
Background:
- Iron deficiency anemia (IDA) is a common nutritional deficiency in children.
- Altered hematological parameters, including platelet count, are observed in IDA.
Purpose of the Study:
- To investigate platelet count variations in children diagnosed with iron deficiency anemia.
- To explore the correlation between platelet count and iron status markers.
- To assess the effect of iron therapy on platelet counts in pediatric IDA.
Main Methods:
- Platelet counts were measured in 30 children with IDA and compared to 40 healthy controls.
- Hemoglobin levels, serum iron, and transferrin saturation were analyzed.
- Changes in platelet count and reticulocyte levels were monitored post-iron therapy.
Main Results:
- Children with IDA exhibited significantly higher platelet counts than controls.
- Platelet count showed a correlation with serum iron levels but not transferrin saturation.
- Iron therapy led to an insignificant decrease in platelet count and an increase in reticulocytes.
Conclusions:
- Elevated platelet counts are a common finding in pediatric iron deficiency anemia.
- Platelet count in IDA is associated with serum iron levels.
- Iron supplementation may help normalize platelet counts in anemic children.