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Related Experiment Videos

Extreme pyrexia

H B Simon

    JAMA
    |November 22, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Extreme pyrexia, defined as temperatures between 41.1 C and 42.2 C, was analyzed in 28 patients. Standard therapies proved effective, with few cases directly attributed to fever, though underlying conditions contributed to mortality.

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    Area of Science:

    • Medicine
    • Clinical Research
    • Internal Medicine

    Background:

    • Extreme pyrexia, characterized by high body temperatures, presents a significant clinical challenge.
    • Understanding the causes and effective management of severe fever is crucial for patient outcomes.

    Purpose of the Study:

    • To retrospectively analyze cases of extreme pyrexia over a five-year period.
    • To identify the primary causes of extreme fever and evaluate the efficacy of standard treatment protocols.

    Main Methods:

    • Retrospective analysis of 28 patient cases with temperatures ranging from 41.1 C to 42.2 C.
    • Review of patient records to determine the etiology of fever and the treatments administered.

    Main Results:

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  • The mean maximum temperature recorded was 41.4 C.
  • Infections and thermoregulatory defects were the main causes of fever.
  • Standard treatments including antipyretics (aspirin, acetaminophen), surface cooling, and volume expansion were generally successful.

    • Conclusions:

    • Direct tissue damage from extreme pyrexia was minimal in the studied cases.
    • While few deaths were directly linked to extreme fever, a significant percentage of patients succumbed to serious underlying diseases.
    • Effective management of extreme pyrexia involves addressing the underlying cause and employing supportive therapies.