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Updated: Jun 29, 2026

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique
Published on: May 3, 2015
A system for the determination of mineralocorticoid activity by electrical potential difference measurements
Abstract:
An electronic measuring instrument, which automatically calculates the rectal potential difference, has been developed to determine mineralocorticoid activity in patients with primaroid disorders. A special probe with a disposable tip enables measurements to be made on successive patients without prior cleaning of the probe. The technique, results and their clinical implications are discussed. A highly significant correlation between plasma aldosterone and rectal potential difference is demonstrated.
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