Prostatic biopsy. A morphologic correlation of aspiration cytology with needle biopsy histology

One hundred and eighteen aspiration biopsies of the prostate are correlated with needle biopsies. The overall accuracy of the needle biospy is 85.6% and that of the aspirates is 86.6%. The author recommends that both techniques should be used simultaneously in the diagnosis of carcinoma of the prostate. Descriptions are given of benign and malignant cell types in prostatic aspirates, with special emphasis on the features differentiating benign atypia of prostatic cells from well-differentiated adenocarcinoma, as this is potentially an important source of false-positive reports in aspiration smears.