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Updated: Aug 16, 2026
The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Susceptibility to lupus nephritis in the NZB/W model system
1Center for Mammalian Genetics Department of Immunology, Pathology, and Laboratory Medicine University of Florida Gainesville FL 32610-0275 USA. morel@ufl.edu
Abstract:
Advances in genetic mapping have resulted in the identification of multiple lupus susceptibility loci in the NZB/W mouse model. The analysis of congenic strains carrying these loci is now providing functional data on their role in lupus pathogenesis and is paving the way to the identification of the susceptibility genes and their molecular characterization.
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