RNA catalysis
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Updated: Oct 26, 2026

Hot Biological Catalysis: Isothermal Titration Calorimetry to Characterize Enzymatic Reactions
Published on: April 4, 2014
1Department of Chemistry and Biochemistry The Center for Molecular Biology of RNA Sinsheimer Laboratories University of California Santa Cruz Santa Cruz CA 95064 USA. wgs@kropotkin.ucsc.edu
Abstract:
Our understanding of the relationship between the structure of RNA and its catalytic activity has advanced significantly in the past year. These advances include time-resolved crystallographic studies on the hammerhead ribozyme, as well as new structures of a group I intron, a lead(II)-cleavage ribozyme, a hepatitis delta virus ribozyme, and components of the spliceosome machinery and the peptidyl transferase center of the ribosome and, most significantly, the structure of the ribosome itself.
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