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Related Experiment Videos

Synchronous bilateral Wilms' tumor

A Nawaz1, C Mpofu, R Shawis

  • 1Division of Paediatric Surgery, Department of Surgery, Tawam Hospital, Al Ain, Abu Dhabi, United Arab Emirates.

Pediatric Surgery International
|January 23, 1999
PubMed
Summary

Synchronous bilateral Wilms

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Area of Science:

  • Pediatric Oncology
  • Nephrology

Background:

  • Synchronous bilateral Wilms' tumor (WT) represents 5% of all WT cases globally.
  • A study of 34 WT cases revealed 7 (20.6%) bilateral cases, with a male predominance in 5 instances.
  • Observed high bilaterality and male preponderance may indicate regional variations in Wilms' tumor presentation.

Purpose of the Study:

  • To report the diagnosis, therapy, and outcomes of synchronous bilateral Wilms' tumor.
  • To investigate potential regional variations in Wilms' tumor characteristics.

Main Methods:

  • Retrospective analysis of 34 Wilms' tumor cases treated.
  • Detailed review of diagnostic procedures.
  • Evaluation of therapeutic strategies, including preoperative chemotherapy.
  • Assessment of patient outcomes.

Main Results:

  • Seven out of 34 (20.6%) Wilms' tumor cases were bilateral.
  • Five of the bilateral cases occurred in males, indicating a male preponderance.
  • The frequency of bilaterality and male predominance in this series differed from international reports.

Conclusions:

  • The findings suggest possible regional variations in the epidemiology of Wilms' tumor.
  • Further research is warranted to understand the factors contributing to these observed differences.

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