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Updated: Jul 29, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Medical treatment of secretory hypophyseal adenomas]
1Clinique des Maladies Endocriniennes et Métaboliques, Hôpital Cochin, Paris.
Abstract:
The main indication for medical treatment of the secretory pituitary adenomas is macroprolactinoma. In this case, bromocriptine therapy obtains better results than surgery, by a life-long administration. New dopaminergic drugs with better tolerance and a longer half-life than bromocriptine will probably improve compliance to treatment. Besides, somatostatin analogs, especially the slowly-released preparations, administrated once or twice per month, often obtain normalization of hormonal production in GH (growth hormone) or TSH (thyrotropin) secreting adenomas after surgical failure and are used in complement to radiotherapy.
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