Related Experiment Videos
Trigeminal chemosensitivity: Differences in relation to the time of the day
J Lötsch1, T Hummel, H G Kraetsch
1Department of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-Nürnberg, Germany. jloetsch@leland.stanford.edu
Chemical Senses
|January 23, 1999
Abstract:
Day-night differences of trigeminal chemosensitivity were investigated in 18 healthy volunteers employing both pain-related cortical potentials and pain ratings in response to stimulation of the nasal mucosa with CO2. Day-night differences were found with N 1 P2 amplitudes, P2 latencies and pain ratings. It is concluded that the time of the day must not be ignored when human chemosensitivity is investigated at suprathreshold levels.