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Glyoxalase I activity in human prostate cancer: a potential marker and importance in chemotherapy
S D Davidson1, J P Cherry, M S Choudhury
1Department of Urology, New York Medical College, Valhalla 10595, USA.
The Journal of Urology
|January 23, 1999
Abstract
Purpose:
To provide information on the activity of Gly-I in prostate cancer.
Materials And Methods:
We performed qualitative Gly-I assay on prostate tissues.
Results:
Gly-I activity between prostate cancer and noncancerous specimens differed substantially and significantly, although such activity also varied somewhat among cancer specimens.
Conclusions:
Gly-I activity is indeed higher in cancerous than in noncancerous specimens, suggesting that it may play a role in prostate cancer homeostasis and survival.
