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Design and characterization of gramicidin channels
D V Greathouse1, R E Koeppe, L L Providence
1Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville 72701, USA.
Methods in Enzymology
|January 23, 1999
Abstract:
This article summarizes methods for the chemical synthesis and biophysical characterization of gramicidins with varying sequences and labels. The family of gramicidin channels has developed into a powerful model system for understanding fundamental properties, interactions, and dynamics of proteins and lipids generally, and ion channels specifically, in biological membranes.