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A new class of pyrrolidin-2-ones: synthesis and pharmacological study. II
C Saturnino1, P Saturnino, A Capasso
1Università degli Studi di Salerno, Facoltà di Farmacia, Salerno, Italy.
Journal De Pharmacie De Belgique
|January 23, 1999
Abstract:
The anticonvulsant activity of a second series of pyrrolidin-2-ones (1-2a, 1-4b, 1-9c) was tested on pentylenetetrazole (PTZ) treated mice. The compounds were obtained by acylation of N-(3'-aminopropyl)-2-pyrrolidinone with the suitable acid chloride.