A molecular blueprint for targeting cancer?

Genetic and epigenetic changes in mammary epithelial cells identify a subpopulation of cells involved in early carcinogenesis.

Cold Spring Harbor symposia on quantitative biology·2006

Minichromosome maintenance protein 2 expression in prostate: characterization and association with outcome after therapy for cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research·2001

Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence.

Journal of mammary gland biology and neoplasia·2001

DNA replication licensing and human cell proliferation.

Journal of cell science·2001

Stromal cells can contribute oncogenic signals.

Seminars in cancer biology·2001

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes.

Nature·2001

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

Nature genetics·2026

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Nature genetics·2026

Correlations between causal effect sizes of proximal SNPs vary with functional annotations and implicate stabilizing selection.

Nature genetics·2026

hnRNPK condensates facilitate enhancer-promoter looping and RNA polymerase II recruitment.

Nature genetics·2026

Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer's disease.

Nature genetics·2026

Prevalence and chronology of colibactin-associated mutational processes and their microbiome spectra in Japanese colorectal cancer.

Nature genetics·2026

Control of Intraocular Metastases of ALK-Rearranged Non-Small Cell Lung Cancer with Sequential Anaplastic Lymphoma Kinase Tyrosine Kinase Inhibitors: A Report of 2 Cases and Review of the Literature.

Case reports in oncology·2026

TP53 mutation drives unique transcriptional and functional vulnerabilities independent of del(17p) in multiple myeloma.

iScience·2026

Immunotherapy Efficacy in SMARC-Altered Cancers: A pan-cancer analysis of clinical outcomes in response to immune checkpoint inhibition.

iScience·2026

Hierarchical ROS-scavenging hydrogel system for coordinating the modulation of RGC necroptosis and oxidative stress in an acute glaucoma model.

Bioactive materials·2026

Does Combination Therapy With a Glucagon-Like Peptide-1 Receptor Agonist and a Sodium-Glucose Cotransporter 2 Inhibitor Enhance Cardiovascular and Renal Protection in People With Type 2 Diabetes Mellitus?

Cureus·2026

Arctigenin discovered by high-throughput screening ameliorates doxorubicin-induced cardiotoxicity as a novel natural KEAP1-NRF2 inhibitor.

Journal of pharmaceutical analysis·2026

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A molecular blueprint for targeting cancer?

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Genetic and epigenetic changes in mammary epithelial cells identify a subpopulation of cells involved in early carcinogenesis.

Minichromosome maintenance protein 2 expression in prostate: characterization and association with outcome after therapy for cancer.

Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence.

DNA replication licensing and human cell proliferation.

Stromal cells can contribute oncogenic signals.

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes.

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Correlations between causal effect sizes of proximal SNPs vary with functional annotations and implicate stabilizing selection.

hnRNPK condensates facilitate enhancer-promoter looping and RNA polymerase II recruitment.

Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer's disease.

Prevalence and chronology of colibactin-associated mutational processes and their microbiome spectra in Japanese colorectal cancer.

Control of Intraocular Metastases of ALK-Rearranged Non-Small Cell Lung Cancer with Sequential Anaplastic Lymphoma Kinase Tyrosine Kinase Inhibitors: A Report of 2 Cases and Review of the Literature.

TP53 mutation drives unique transcriptional and functional vulnerabilities independent of del(17p) in multiple myeloma.

Immunotherapy Efficacy in SMARC-Altered Cancers: A pan-cancer analysis of clinical outcomes in response to immune checkpoint inhibition.

Hierarchical ROS-scavenging hydrogel system for coordinating the modulation of RGC necroptosis and oxidative stress in an acute glaucoma model.

Does Combination Therapy With a Glucagon-Like Peptide-1 Receptor Agonist and a Sodium-Glucose Cotransporter 2 Inhibitor Enhance Cardiovascular and Renal Protection in People With Type 2 Diabetes Mellitus?

Arctigenin discovered by high-throughput screening ameliorates doxorubicin-induced cardiotoxicity as a novel natural KEAP1-NRF2 inhibitor.

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A molecular blueprint for targeting cancer?

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