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Bactericidal activity of lansoprazole and three macrolides against Helicobacter pylori strains tested by the
M T Fera1, M Carbone, A De Sarro
1Istituto di Microbiologia, Facoltà di Medicina e Chirurgia, Università di Messina, Italy. Teti@eniware.it
International Journal of Antimicrobial Agents
|January 23, 1999
Abstract:
The bactericidal activities of macrolides (clarithromycin, roxithromycin and azithromicyn) and lansoprazole, alone and in combination, against Helicobacter pylori strains were evaluated. It was found that the association of lansoprazole and clarithromycin resulted in a marked synergism, while the combination of roxithromycin or azithromycin with lansoprazole had synergistic and additive effects.