Related Experiment Videos
Vismiaphenones D-G, new prenylated benzophenones from Vismia cayennensis
R W Fuller1, C K Westergaard, J W Collins
1Laboratory of Drug Discovery Research and Development, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, NCI-FCRDC, Bldg. 1052, Room 121, Frederick, Maryland 21702-1201, USA.
Journal of Natural Products
|January 23, 1999
Abstract:
Following anti-HIV bioassay-guided fractionation, four new prenylated benzophenones, vismiaphenones D-G (7-10), were isolated from extracts of leaves of Vismia cayennensis. The structures were elucidated by spectral analyses. Only vismiaphenone D (7) exhibited HIV-inhibitory activity in the NCI primary screen.