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The structure of mithramycin reinvestigated
S E Wohlert1, E Künzel, R Machinek
1Medical University of South Carolina, Department of Pharmaceutical Sciences, 171 Ashley Avenue, Charleston, South Carolina 29425-2303, USA.
Journal of Natural Products
|January 23, 1999
Abstract:
A reinvestigation of the structure of mithramycin, the principal product of Streptomyces argillaceus ATCC 12956, is reported. The structure elucidation was carried out with mithramycin decaacetate (4) using 2D NMR methods, including TOCSY, HMBC, and HSQC experiments. The work resulted in structure 3being confirmed for mithramycin.