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A new biologically active acylated triterpene saponin from Silene fortunei
M A Lacaille-Dubois1, B Hanquet, Z H Cui
1Laboratoire de Pharmacognosie, Faculté de Pharmacie, Université de Bourgogne, 7, Bd. Jeanne d'Arc, 21033 Dijon Cedex, France. malacd@u-bougogne.fr
Abstract:
A new acylated triterpene-saponin (1), together with a mixture of the known jenisseensosides C and D, has been isolated from the roots of Silene fortunei. The structure of the new compound was established by chemical means and spectroscopic methods as 3-O-[beta-D-galactopyranosyl-(1-->2)-beta-D-glucuronopyranosyl]-28 -O- [[alpha-L-arabinopyranosyl-(1-->2)-alpha-L-arabinopyranosyl- (1-->3)-b eta-D-xylopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->2)]-[beta-D- glucopyranosyl-(1-->3)]-4-O-acetyl-beta-D-fucopyranosyl]quillaic acid. This saponin showed a significant enhancement of granulocyte phagocytosis in vitro.