Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Blood conservation in hip trauma

A H Schmidt1, D C Templeman, R F Kyle

  • 1Department of Orthopedic Surgery, Hennepin County Medical Center, Minneapolis, MN 55415, USA.

Clinical Orthopaedics and Related Research
|January 26, 1999
PubMed
Summary

Hip fracture patients often need transfusions due to blood loss. Erythropoietin therapy and iron replacement can help manage blood loss and reduce transfusion needs in these critical surgical cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of coronal plane angulation on patient reported outcome measures of operatively treated distal femur fractures: A multi-center prospective evaluation.

Injury·2024
Same author

Blood group A epitopes do not facilitate entry of SARS-CoV-2.

Journal of internal medicine·2021
Same author

HLA-E typing of more than 2.5 million potential hematopoietic stem cell donors: Methods and population-specific allele frequencies.

Human immunology·2021
Same author

Evolution of MNC and lymphocyte collection settings employing different Spectra Optia<sup>®</sup> Leukapheresis systems.

Vox sanguinis·2017
Same author

Dual redundant sequencing strategy: Full-length gene characterisation of 1056 novel and confirmatory HLA alleles.

HLA·2017
Same author

TypeLoader: A fast and efficient automated workflow for the annotation and submission of novel full-length HLA alleles.

HLA·2017

Area of Science:

  • Orthopedic Surgery
  • Hematology

Background:

  • Hip and pelvic fractures cause significant blood loss during injury and surgery.
  • The emergent nature of fracture surgery limits preoperative optimization and blood donation.
  • Allogeneic blood transfusions, while necessary, increase infectious complication risks.

Purpose of the Study:

  • To discuss blood loss management strategies for hip fracture patients.
  • To evaluate the role of iron replacement and erythropoietin therapy.

Main Methods:

  • Review of experience with blood loss management in hip injury patients.
  • Implementation of aggressive iron (Fe) replacement therapy.
  • Utilization of recombinant human erythropoietin (EPO) to stimulate hematopoiesis.

Related Experiment Videos

Main Results:

  • Erythropoietin therapy has demonstrated efficacy in stimulating red blood cell production.
  • Aggressive iron replacement is a key component of managing anemia.
  • These strategies aim to minimize the need for allogeneic blood transfusions.

Conclusions:

  • Effective blood loss management in hip fractures requires a multi-faceted approach.
  • Iron and erythropoietin therapies are valuable tools in reducing transfusion requirements.
  • Optimizing hematopoiesis can improve patient outcomes and reduce transfusion-related risks.