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Lipid hydroperoxide analysis by high-performance liquid chromatography with mercury cathode electrochemical detection
W Korytowski1, P G Geiger, A W Girotti
1Department of Biochemistry, Medical College of Wisconsin, Milwaukee 53226, USA.
Methods in Enzymology
|January 27, 1999
Abstract:
In addition to the applications described, HPLC-EC(Hg) can be used for determining LOOHs in lipoproteins and for monitoring LOOH detoxification in cells. As it continues to be developed and refined, this approach should prove to be valuable not only for ultrasensitive determination of lipid-derived peroxides, but protein- and nucleic acid-derived peroxided as well.