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Cholinesterase reactivators - contribution to the study of their metabolic effects
O Benesová1, J Hvizdosová, J Musil
1Institute of Pharmacology, Medical Faculty of Hygiene, Charles University, Praha (Czechoslovakia).
Abstract:
Cholinesterase reactivators - trimedoxim, methoxim and obidoxim - injected in the dose of 20 mg/kg s.c., increase muscle glycogen concentration in normal, but not in adrenalectomized rats. This effect may be in connection with simoultaneously found rise of serum corticosteron level. Trimedoxim decreases adrenaline, methoxim and obidoxim noradrenaline concentration in adrenals.