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[Relation of the pressure-volume loop and mechanical energy properties of the left ventricle]
Z Popović1, M Mirić, P Otasević
1Dedinje Cardiovascular Institute, Belgrade.
Abstract:
New biomechanical models of the left ventricle, as well as recent technological breakthroughs, allowed a wider use of pressure/volume loop in the assessment of mechano-energetic properties of the left ventricle. The most widely used parameter derived from the pressure/volume loop is end-systolic elastance, which reflects the left ventricular contractility. Additionally, pressure/volume loop has been proved to be useful in the assessment of left ventricular diastolic function. More complex parameters of left ventricular mechanisms, such as stroke work and potential energy, can be studied by plotting pressure/volume loop and lines depicting end-systolic and end-diastolic pressure/volume relations. Similarly, the ratio of the area contained in the pressure/volume loop, that is stroke work, and the level of myocardial oxygen consumption can be used in the assessment of the efficiency by which the left ventricle converts chemical energy into mechanical energy. In conclusion, the use of pressure/volume loop and its relationship to myocardial oxygen consumption can be very effective in the analysis of cardiovascular performance in various settings.