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Updated: Aug 14, 2026

Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
Published on: October 27, 2009
[Effect of electrical stimulation of the hypothalamus on the process of blood platelet aggregation]
Abstract:
Stimulation of hypothalamic ventromedial and posterior nuclei via implanted electrodes was followed by phasic changes of the blood coagulation processes and thrombocytes dynamic functions. Within the first minutes after stimulation, an increase of the blood coagulation potential, of aggregation and adhesive features of thrombocytes was observed, replaced later by reduction of thrombocytes dynamic features and by decreasing blood coagulation potential. The above changes are associated with alteration of the blood content of aggregating agents, inhibitors of aggregation, and blood coagulating factors. The hypothalamic structures are suggested to exert control over thrombocytes hemostatic functions via a humoral link.
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