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Published on: May 21, 2017
Comparison of long term outcome in patients with or without aortic ring abscess treated surgically for aortic valve
N Danchin1, G Retournay, O Stchepinsky
1Service de Cardiologie, CHU Nancy-Brabois, 54500 Vandoeuvre-lès-Nancy, France. n.danchin@chu-nancy.fr
Objective:
To assess the long term prognostic significance of aortic valve ring abscess in patients with aortic endocarditis.
Patients:
A consecutive series of 75 patients who had surgery for aortic infective endocarditis between 1981 and 1989; 35 had aortic ring abscesses (group 1) and 40 did not (group 2). Mean age did not differ between the two groups. Prosthetic valve endocarditis was present in 17% of group 1 and 5% of group 2. Pneumococcal or beta haemolytic streptococcal endocarditis was more common in patients with native valve endocarditis who had aortic ring abscesses (20% v 5%).
Design:
Cohort analysis.
Results:
In-hospital mortality (11.4% v 7.5%) and 10 year survival (56% v 66%) were not significantly different between groups 1 and 2. In patients with native valve endocarditis, 10 year survival was 62% and 66%, respectively for patients with or without ring abscess, and 10 year reintervention-free survival was 38% v 58% (p = 0.11). In these patients, the presence of an intercurrent illness, severe congestive heart failure before surgery, and use of valved conduits for surgical treatment were predictors of poorer long term survival. At follow up residual aortic regurgitation was documented in 72% of patients in group 1 and 26% in group 2 (p < 0.01).
Conclusions:
Aortic valve ring abscess is not an independent marker of poor long term outcome in patients with infective endocarditis. However, as residual aortic regurgitation appears frequent at follow up, specific surgical techniques should be considered in patients with paravalvar abscesses.
Insights
Aortic valve ring abscesses in infective endocarditis patients do not independently predict poor long-term survival. However, increased residual aortic regurgitation necessitates specialized surgical approaches for paravalvular abscesses.
Area of Science:
- Cardiovascular Surgery
- Infectious Diseases
- Clinical Prognostics
Background:
- Infective endocarditis (IE) can lead to serious complications, including aortic valve ring abscesses.
- The prognostic significance of aortic ring abscesses in IE patients remains a subject of investigation.
Purpose of the Study:
- To evaluate the long-term prognostic impact of aortic valve ring abscesses in patients undergoing surgery for aortic infective endocarditis.
Main Methods:
- A cohort analysis of 75 patients who underwent surgery for aortic IE between 1981 and 1989.
- Patients were divided into two groups: 35 with aortic ring abscesses and 40 without.
- Data on in-hospital mortality, long-term survival, and reintervention-free survival were analyzed.
Main Results:
- No significant difference in in-hospital mortality or 10-year survival between patients with and without aortic ring abscesses.
- Patients with native valve endocarditis and ring abscesses showed a trend towards lower 10-year reintervention-free survival (38% vs. 58%).
- Residual aortic regurgitation was significantly more frequent in patients with ring abscesses (72% vs. 26%) at follow-up.
Conclusions:
- Aortic valve ring abscess is not an independent predictor of poor long-term outcome in patients with infective endocarditis.
- The high incidence of residual aortic regurgitation in patients with paravalvular abscesses suggests the need for tailored surgical techniques.
Related Concept Videos
Aortic Regurgitation I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation III: Medical Management
Endocarditis I: Introduction
Endocarditis III: Medical Management
Aneurysm III: Interprofessional Care

