Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Choice of an antidepressive agent]

A Pham-Scottez¹

¹Service de Psychiatrie, Hôpital Paul Brousse, Villejuif.

Presse Medicale (Paris, France : 1983)

|January 29, 1999

Summary

Choosing antidepressants requires more than just understanding their mechanisms. Patient-specific clinical features and the patient-physician relationship are crucial for effective depression treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[About a first brief psychotic episode at 57 in a context of COVID-19 infection].

L'Encephale·2022

Same author

Attention-deficit/hyperactivity disorder symptoms and psychological comorbidity in eating disorder patients.

Eating and weight disorders : EWD·2017

Same author

Borderline personality disorder and mental healthcare service use among adolescents.

Journal of personality disorders·2013

Same author

Body dissatisfaction is improved but the ideal silhouette is unchanged during weight recovery in anorexia nervosa female inpatients.

Eating and weight disorders : EWD·2012

Same author

The level of associated depression and anxiety traits improves during weight regain in eating disorder patients.

Eating and weight disorders : EWD·2012

Same author

Factors predictive of ten-year mortality in severe anorexia nervosa patients.

Acta psychiatrica Scandinavica·2010

Area of Science:

Pharmacology
Neuroscience
Psychiatry

Context:

The development of new antidepressant agents has expanded treatment options.
Over 20 antidepressant compounds were available by 1998, exhibiting diverse mechanisms of action.

Purpose:

To highlight the limitations of solely relying on drug mechanisms for depression classification and treatment selection.
To emphasize the importance of integrating clinical and functional patient features into therapeutic decisions.

Summary:

Knowledge of individual antidepressant compounds and their effects on brain monoamines is insufficient for a pharmacoclinical depression classification.
The mechanism of action alone does not guide the selection of the optimal antidepressant for a specific patient.
Therapeutic choices must incorporate the patient's clinical and functional presentation.

Impact:

This approach underscores the need for personalized medicine in depression treatment.
It emphasizes the critical role of the patient-physician relationship in managing depressive states.
Facilitates more informed and effective antidepressant selection for improved patient outcomes.

Related Experiment Videos