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[The resistance of Propionibacterium acnes and Staphylococcus epidermidis to cyclines. The Research and Study Group
V Noyon1, F Legallou, H Richet
1Laboratoire de Bactériologie, Virologie, Immunologie, CHU, Nantes.
Background:
A rising percentage of tetracycline-resistant Propionibacterium acnes strains has been reported in the English literature.
Patients And Methods:
We studied a population of 16 patients with acne who had been treated with oral tetracyclines during the preceding year. A bacteriological examination of a skin biopsy was obtained in all patients to determine aerobic and anaerobic flora as wells as resistance to tetracycline and minocycline.
Results:
Staphylococcus epidermidis strains were frequently resistant to tetracycline (87.5%) as well as minocycline (30%). Tetracycline-resistant Propionibacterium acnes were also observed (7%). Inversely, we were unable to evidence any minocycline-resistant Propionibacterium acnes strains.
Conclusion:
These findings emphasize the importance of determining whether therapeutic response is related or not to the presence of resistant strains.
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