Perspectives on prognosis of soft tissue musculoskeletal disorders

This paper reflects on the state of evidence related to the prognosis of soft tissue musculoskeletal disorders. Prediction of the likely clinical course, duration and outcomes for individuals with such disorders is an important task of rehabilitation clinicians. Criteria used to evaluate the validity of evidence on prognosis are reviewed. Application of these criteria to the literature on three soft tissue disorders reveals methodological weaknesses in the majority of existing studies. Yet strengthening the rigour of future research according to clinical epidemiological criteria may not capture the important factors which prolong disability in individuals with soft tissue injuries. Specific considerations related to case definitions, prognostic factors, study design, conceptual frameworks and study setting are recommended.