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Cyclic vomiting syndrome in South-East Asian children
1Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
Insights
Cyclic vomiting syndrome (CVS) in South-East Asian children presents similarly to other populations, though specific features and triggers may vary. Current therapies for acute attacks and prevention were ineffective in this cohort.
Area of Science:
- Pediatrics
- Gastroenterology
- Clinical Medicine
Background:
- Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent episodes of intense nausea and vomiting.
- Understanding the clinical presentation in diverse geographic regions is crucial for accurate diagnosis and management.
Purpose of the Study:
- To delineate the clinical characteristics, therapeutic approaches, and outcomes of pediatric patients diagnosed with cyclic vomiting syndrome in Southeast Asia.
Main Methods:
- A retrospective review was conducted on pediatric patients meeting CVS diagnostic criteria.
- Data were collected from two Malaysian centers between 1987 and 1997.
Main Results:
- Eight children (5 female, 3 male) diagnosed with CVS were identified.
- Patients experienced cyclical, self-limiting vomiting episodes with symptom-free intervals; mean age of onset was 5.9 years.
- Clinical features largely mirrored those reported in international literature, with stress noted as a trigger in two cases; therapies were ineffective.
Conclusions:
- Pediatric CVS in Southeast Asia shares commonalities with descriptions in global literature.
- Notable differences may exist, warranting further investigation into regional variations of CVS.
Objective:
To describe the clinical features, management and outcome of children with cyclic vomiting syndrome (CVS) from South-East Asia.
Methodology:
Retrospective review of all children who fulfilled the diagnostic criteria of CVS and who were seen at Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur and Paediatric Unit, Penang Hospital, Penang, Malaysia from 1987 to 1997.
Results:
Eight children with CVS were seen at the two units during the study period, five girls and three boys. All had cyclical, self-limited episodes of nausea and vomiting with symptom-free intervals. The mean age of onset was 5.9 years. The clinical features were similar to other series described in the literature. Only two of the eight children were described as 'perfectionist'. Two children identified stress as precipitating factors. Therapy to reduce the number of emeses during acute attacks and to prevent subsequent attacks had been ineffective.
Conclusion:
There are similarities and differences in CVS from South-East Asian children as compared to those described in the literature.