Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Effects of Radiation02:59

Biological Effects of Radiation

All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they produce ions...
Dose Size and Dosing Frequency: Determination Methods01:21

Dose Size and Dosing Frequency: Determination Methods

Determining the optimal dose size and dosing frequency in pharmacotherapy is crucial for achieving therapeutic effectiveness while minimizing adverse effects. This article explores the methodologies employed in determining these parameters, focusing on their significance and interplay to tailor dosing regimens.Dose Size: Dose size refers to the amount of a drug administered in a single dose. It is determined based on the drug's pharmacodynamics and pharmacokinetics properties and...
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses01:25

Determination of Multiple Dosing Parameters: Loading and Maintenance Doses

A loading dose is an essential pharmacological strategy to rapidly achieve the target plasma drug concentration necessary for an immediate therapeutic effect. This approach is especially critical for drugs characterized by slow absorption or extended half-lives, where delaying therapeutic plasma levels could compromise treatment outcomes. By administering a loading dose, clinicians ensure a prompt onset of drug action, even for agents with complex pharmacokinetic profiles.Achieving steady-state...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of secreted and membrane-bound mucins in the airways of piglets experimentally infected with Mycoplasma hyopneumoniae.

Veterinary journal (London, England : 1997)·2011
Same author

Expression of RUNX3 in skin cancers.

Clinical and experimental dermatology·2011
Same author

Malignant melanoma of the vulva: an extension of cutaneous melanoma?

Gynecologic oncology·2011
Same author

Molecular inflammation as an underlying mechanism of the aging process and age-related diseases.

Journal of dental research·2011
Same author

Comparative efficacy of commercial Mycoplasma hyopneumoniae and porcine circovirus 2 (PCV2) vaccines in pigs experimentally infected with M. hyopneumoniae and PCV2.

Vaccine·2011
Same author

Target structure induced suppression of the ionization cross section for very low energy antiproton-hydrogen collisions.

Physical review letters·2011

Related Experiment Video

Updated: Jul 21, 2026

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator
07:31

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator

Published on: May 9, 2014

Calculation of effective doses for broad parallel photon beams

C H Kim1, W D Reece, J W Poston

  • 1Department of Nuclear Engineering, Texas A&M University, College Station 77843-3133, USA.

Health Physics
|February 3, 1999
PubMed
Summary

This study calculated effective dose (E) using MCNP simulations, finding it consistently lower than dose equivalent (H(E)). Results suggest H(E) can serve as a conservative estimate for E in radiation dosimetry.

More Related Videos

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Related Experiment Videos

Last Updated: Jul 21, 2026

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator
07:31

Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator

Published on: May 9, 2014

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

  • Medical Physics
  • Radiation Dosimetry
  • Computational Physics

Background:

  • Effective dose (E) is crucial for radiation protection and risk assessment.
  • Accurate calculation of E requires considering various irradiation geometries.
  • Existing dose equivalent (H(E)) values are often used as a proxy for E.

Purpose of the Study:

  • To calculate effective dose (E) for broad parallel photon beams across all incident directions.
  • To compare calculated E with dose equivalent (H(E)) values.
  • To propose improvements for personal dosimeter angular response.

Main Methods:

  • Utilized the Monte Carlo N-Particle (MCNP) transport code.
  • Employed a hermaphroditic phantom for dose calculations.
  • Analyzed conversion coefficients from air kerma to effective dose.

Main Results:

  • Effective dose (E) was consistently found to be less than dose equivalent (H(E)) for all beam directions and energies.
  • Differences between E and H(E) were generally insignificant, except for overhead and underfoot beam incidence.
  • Proposed ideal angular response factors for personal dosimeters based on E and H(E) distributions.

Conclusions:

  • Current H(E) values can be interpreted as E or a conservative estimate, simplifying dosimetry without detailed geometry.
  • The findings support the use of H(E) in radiation protection, with awareness of specific directional exceptions.
  • The proposed angular response factors can enhance the accuracy of personal dosimeters for diverse photon beam exposures.