Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

MHCWeb: converting a WWW database into a knowledge-based collaborative environment

L Hon1, N F Abernethy, V Brusic

  • 1Stanford Medical Informatics, Stanford University, CA 94305-5479, USA. hon@smi.stanford.edu

Proceedings. AMIA Symposium
|February 3, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Precise clinical classification of metabolic associated fatty liver disease].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2026
Same author

Protective effect of Angelica sinensis polysaccharide (asp) on cryopreservation-induced damage to semen of chongming white goats.

Cryo letters·2025
Same author

[Clinicopathological and molecular genetic characteristics of ELOC mutated renal cell carcinoma].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2023
Same author

Prevalence, drivers and surveillance of antibiotic resistance and antibiotic use in rural China: Interdisciplinary study.

PLOS global public health·2023
Same author

[Advances in molecular pathogenetic characteristics of clear cell papillary renal tumor].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2023
Same author

[Antibacterial mechanism of Brevinin-2GHk, an antimicrobial peptide from <i>Fejervarya limnocharis</i> skin].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2021
Same journal

Progressive display of very high resolution images using wavelets.

Proceedings. AMIA Symposium·2002
Same journal

The Chronus II temporal database mediator.

Proceedings. AMIA Symposium·2002
Same journal

Gene expression levels in different stages of progression in oral squamous cell carcinoma.

Proceedings. AMIA Symposium·2002
Same journal

An assessment of the visibility of MeSH-indexed medical web catalogs through search engines.

Proceedings. AMIA Symposium·2002
Same journal

Filtering for medical news items using a machine learning approach.

Proceedings. AMIA Symposium·2002
Same journal

Enriching the structure of the UMLS semantic network.

Proceedings. AMIA Symposium·2002
See all related articles

Knowledge bases offer a better way to manage complex scientific data online. The OWEB architecture provides a flexible system for organizing and accessing immunological data, improving usability for researchers.

Area of Science:

  • Bioinformatics
  • Data Management
  • Immunology

Background:

  • Traditional web data resources (flat files, relational databases) struggle with complex, multi-relational scientific data.
  • Existing methods are cumbersome for intricate data models, limiting efficient data distribution and retrieval.

Purpose of the Study:

  • To introduce the OWEB architecture for building online scientific data resources using knowledge bases.
  • To demonstrate the application of OWEB by translating the MHCPEP immunological database into MHCWeb.

Main Methods:

  • Developed the OWEB architecture, a framework for structuring scientific data with secure access and computational modules.
  • Created a conceptual model and controlled terminology for the MHCPEP database.
  • Translated existing MHCPEP data into the OWEB structure, forming the MHCWeb system.

Related Experiment Videos

Main Results:

  • The OWEB architecture enables the creation of robust online scientific data resources.
  • MHCWeb provides flexible data access for both users and computational programs.
  • Successfully translated a complex immunological database into a knowledge-based system.

Conclusions:

  • Knowledge-based resources, like OWEB, are superior for managing complex scientific data compared to traditional methods.
  • The OWEB architecture facilitates flexible and efficient access to scientific data, enhancing research capabilities.
  • OWEB represents a significant advancement in online scientific data resource development, particularly for complex domains like immunology.